Pozor, data utkání jsou orientační.
| 22.08.20 | Přátelský zápas | Blackpool FC | V | Preview | 3:3 | |
| 05.09.20 | Přátelský zápas | Preston North End | D | Preview | 2:0 | |
| 13.09.20 | Premier League | 1. kolo | Tottenham Hotspur | V | Preview | 1:0 |
| 16.09.20 | Ligový pohár | 2. kolo | Salford City | D | Preview | 3:0 |
| 19.09.20 | Premier League | 2. kolo | West Bromwich Albion | D | Preview | 5:2 |
| 23.09.20 | Ligový pohár | 3. kolo | Fleetwood Town | V | Preview | 5:2 |
| 26.09.20 | Premier League | 3. kolo | Crystal Palace | V | Preview | 2:1 |
| 30.09.20 | Ligový pohár | 4. kolo | West Ham United | D | Preview | 4:1 |
| 03.10.20 | Premier League | 4. kolo | Brighton & Hove Albion | D | Preview | 4:2 |
| 17.10.20 | Premier League | 5. kolo | Liverpool FC | D | Preview | 2:2 |
| 24.10.20 | Premier League | 6. kolo | Southampton FC | V | Preview | 0:2 |
| 31.10.20 | Premier League | 7. kolo | Newcastle United | V | Preview | 1:2 |
| 07.11.20 | Premier League | 8. kolo | Manchester United | D | Preview | 1:3 |
| 22.11.20 | Premier League | 9. kolo | Fulham FC | V | Preview | 3:2 |
| 28.11.20 | Premier League | 10. kolo | Leeds United | D | Preview | 0:1 |
| 05.12.20 | Premier League | 11. kolo | Burnley FC | V | Preview | 1:1 |
| 12.12.20 | Premier League | 12. kolo | Chelsea FC | D | Preview | 1:0 |
| 16.12.20 | Premier League | 13. kolo | Leicester City | V | Preview | 2:0 |
| 19.12.20 | Premier League | 14. kolo | Arsenal FC | D | Preview | 2:1 |
| 23.12.20 | Ligový pohár | Čtvrtfinále | Manchester United | D | Preview | 0:2 |
| 26.12.20 | Premier League | 15. kolo | Sheffield United | V | Preview | 1:0 |
| 28.12.20 | Premier League | 16. kolo | Manchester City | D | Preview | odl. |
| 02.01.21 | Premier League | 17. kolo | West Ham United | D | Preview | 0:1 |
| 09.01.21 | FA Cup | 3. kolo | Rotherham United | D | Preview | 2:1e |
| 12.01.21 | Premier League | 18. kolo | Wolverhampton Wanderers | V | Preview | 2:1 |
| 17.01.21 | Premier League | 19. kolo | Aston Villa | V | – | odl. |
| 24.01.21 | FA Cup | 4. kolo | Sheffield Wednesday | D | Preview | 3:0 |
| 27.01.21 | Premier League | 20. kolo | Leicester City | D | Preview | 1:1 |
| 30.01.21 | Premier League | 21. kolo | Newcastle United | D | Preview | 0:2 |
| 03.02.21 | Premier League | 22. kolo | Leeds United | V | Preview | 2:1 |
| 06.02.21 | Premier League | 23. kolo | Manchester United | V | Preview | 3:3 |
| 10.02.21 | FA Cup | 5. kolo | Tottenham Hotspur | D | Preview | 5:4e |
| 14.02.21 | Premier League | 24. kolo | Fulham FC | D | Preview | 0:2 |
| 17.02.21 | Premier League | 16. kolo | Manchester City | D | Preview | 1:3 |
| 20.02.21 | Premier League | 25. kolo | Liverpool FC | V | Preview | 2:0 |
| 01.03.21 | Premier League | 26. kolo | Southampton FC | D | Preview | 1:0 |
| 04.03.21 | Premier League | 29. kolo | West Bromwich Albion | V | ||
| 08.03.21 | Premier League | 27. kolo | Chelsea FC | V | ||
| 13.03.21 | Premier League | 28. kolo | Burnley FC | D | ||
| 20.03.21 | FA Cup | 6. kolo | Manchester City | D | ||
| 03.04.21 | Premier League | 30. kolo | Crystal Palace | D | ||
| 10.04.21 | Premier League | 31. kolo | Brighton & Hove Albion | V | ||
| 17.04.21 | Premier League | 32. kolo | Tottenham Hotspur | D | ||
| 24.04.21 | Premier League | 33. kolo | Arsenal FC | V | ||
| 01.05.21 | Premier League | 34. kolo | Aston Villa | D | ||
| 08.05.21 | Premier League | 35. kolo | West Ham United | V | ||
| 11.05.21 | Premier League | 36. kolo | Sheffield United | D | ||
| 15.05.21 | Premier League | 37. kolo | Wolverhampton Wanderers | D | ||
| 23.05.21 | Premier League | 38. kolo | Manchester City | V |
